Any information something like "calcification mechanism" within bone? Or any adjectives join?

I know what calcification is. But i don't know how does it happen?!
salamss2003@yahoo.com
ekardeh@gamil.com
thank you vm Please write down that a better term would be mineralization. Calcification can be applied to the pathological increase of calcium phosphate in tissues (i.e calcification of arterial plaques) while mineralization is a average process where calcium phosphate crystals hoard and grow in specific tissues (i.e bone). I put together the distinction because the process can occur by different mechanism.
Bone mineral is initially deposited at discrete sites in the collagenous matrix. The initial sites of mineralization are the “hole” zone between the collagen fibrils. There is still debate as to whether bone mineral forms concurrently in the protected environment of membrane bound bodies set as extracellular matrix vesicles, as it does in calcifying cartilage and mineralizing turkey tendons. Because the body fluids are undersaturated near respect to apatite (i.e., apatite will not precipitate spontaneously), the bone matrix must contain one or more components that facilitate apatite deposition.
As bone matures, the mineral crystals become larger and more immaculate (containing fewer impurities). The increase contained by crystal dimension is due both to the actual addition of ions to the crystals (crystal growth) and to aggregation of the crystals.
Bone growth is primarily the work of osteoblasts (or transformed osteoblasts call osteocytes), specialized cells that can control mineral deposition.
Bone deposition is controlled by hormonal controls of the osteocytes.